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Acne drug1 800 Doctors www.1800doctors.com 911 Skin Acne Information www.911skin.com A D D www.aad.org/public/ Acne pages.prodigy.net Acne scars. Derm Net NZ dermnetnz.org Acne - Cosmetic Clinic www.blushworld.com Acne - Scar Treatment - Dermatology Channel www.dermatologychannel.net Acne Scars www.dermadoctor.com Acne 911 www.acne911.com Acne Advice - Clear Skin Book www.acne-advice.com Acne Assassin www.acneassasin.com Acne Blemish Control www.acneblemishcontrol.com Acne Book that is Online www.freeacnebook.com Acne Cares www.acnecares.com Acne Circle www.acnecircle.com Acne Clear up www.acneclearup.com Acne Control www.acnecontrol.net Acne Cure ebooks www.badraunconsulting.com Acne Cured the E-Book www.acnecured.com acne cures revealed www.acnecuresrevealed.net Acne Days www.acnedays.com Acne doctor www.acnedoctor.com Acne Doctor - Adult Acne Treatment www.acnedoctor.com/adult Acne drug www.acne-drug.com Acne Ease is herbal treatment www.acnease.com Acne Eliminated Proactiv www.acne-eliminated.com Acne Elimination www.acneelimination.com/ Acne Free in 3 days www.acnefreein3days.com Acne Freedom www.acne-freedom.com Acne from InteliHealth www.intelihealth.com acne guide www.acneguide.com Acne Healer www.acne-healer.com Acne Helper www.acnehelper.com Acne Info - Product Review www.acneinfo.org Acne Information www.medicinenet.com Acne Information www.acneinformation.org Acne Information Forum www.absoluteacneinfo.com Acne Less www.acneless.com Acne Links www.acnelinks.com Acne Ltd www.acne-ltd.com Acne Medicine www.emaxhealth.com Acne Org - The Regimen www.acne.org Acne Pain and Acne Facts www.acnepain.com Acne Products www.home-remedies-for-you.com Acne Products Site www.acne-products-site.com acne resource www.acne-resource.org Acne resource and treatments www.acne.net Acne Review www.AcneLinks.org Acne Scar Treatments: Acne Scar Treatment Products www.acne-site.com Acne Scarring and Acne Scar Treatment Removal zenmed.com Acne Scars dermatology.about.com Acne scars www.acne.org/scars.php Acne Scars - Treatment and Removal www.acne-online-us.gb.com Acne Scars, Acne Treatment, Stretch Marks abateacne.com Acne Scars, Scar Removal, Scar Treatment and www.kelocote.com Acne Site www.acne-site.com Acne Skin Guide www.acneskinguide.com Acne Support Group - UK www.m2w3.com Acne Tab www.acne-tab.com Acne Therapy Using Medical Microbes www.probiotic-lab.com Acne Treatment - Jude Medical Center www.charmingskin.com Acne Treatment Clinic www.acnetreatment.com Acne Treatment review www.acnelinks.org/treatment Acne Treatment system www.clear-your-acne.com Acne treatments www.mibokspa.com Acne vulgaris http://en.wikipedia.org/wiki/Acne Acne Zits www.acne-zits.com Acne: Acne scars www.ivillage.co.uk Actimine Site www.usmedicalresearch.org Adult Acne www.adult-acne.org/ American Academy of Dermatology www.aad.org American Academy of Family Physicians www.aafp.org American Medical Association www.ama-assn.org American Society for Dermatologic Surgery www.asds-net.org aocd.org www.aocd.org B5 Supplements www.b5supplements.com Beat psoriasis UVB light www.beatpsoriasis.com Bio Skin Care www.bioskincare.com Can Acne Scars Be Removed? www.kidshealth.org Canoe Talk surgery Chronic Acne www.canoe.talksurgery.com Choice Trust www.choicetrust.com Clear Acne Treatment Program www.clearadultskin.com Clear Complexion www.clearcomplexions.com Clear skin Net Acne & Skincare www.clearskin.net Clearogen www.clearogen.com/ Clearogen Acne Treatment www.clearogen.com cosmetic surgery news - acne scars www.cosmeticsurgery-news.com Cure Acne UK www.cure-acne.co.uk Curing Acne and Acne Treatments www.curing-acne.com Derm Store www.dermstore.com Dermatology http://en.wikipedia.org/wiki/Dermatology Dermatology About dermatology.about.com Dermatology Co UK - Acne www.dermatology.co.uk Dermatology Doctor Shop www.dermatologydocshop.com Dermnetnz Acne Scarring www.dermnetnz.org Dermystique 4-Step Acne www.dermystique.com DIY Medical Knowledge www.diy-medical-knowledge.com Doctor's Guide www.docguide.com Doctors Secrets www.doctorsecrets.com/ Drugstore . Com www.drugstore.com Eczema and Acne Herbs articles.pointshop.com Emedicine Health www.emedicinehealth.com Euromeds Renova www.euromeds.co.uk/acne Family doctor org www.familydoctor.og Fashion Beauty Acne Corner www.fashion-beauty.com Garlic Central www.garlic-central.com Great skin Store www.greatskin.com Health cyclopedia www.healthcyclopedia.com Health finder www.healthfinder.gov health scout www.healthscout.com Healthopedia www.healthopedia.com/ Herbal soap for Acne www.facefriend.com Home Laser www.skincarelaser.com i Enhance includes Dermatologist www.ienhance.com In House Pharmacy www.inhousepharmacy.com Includes some Acne Products www.productwatch.net Information and Humor www.skinema.com International Rosacea Foundation www.internationalrosaceafoundation.org Keloideloid http://en.wikipedia.org/wiki/Keloid Knowledge Teen Acne www.knowledge.com Lalisse Acne & Pimple Solution Product www.lalisse.com Locate a Doctor www.locateadoc.com mayoclinic www.mayoclinic.com Medem Network www.medem.com Medical Encyclopedia Acne www.nlm.nih.gov Medicare Locator www4.medicare.gov Medline Information on Acne (National Library) www.nlm.nih.gov/medlineplus Melanoma http://en.wikipedia.org/wiki/Malignant_melanoma Milksucks - Milk and Acne www.milksucks.com Models Style www.models-style.com my DR Australian www.mydr.com.au/ National Institutes of Health (NIH) - Acne www.niams.nih.gov Native Remedies www.nativeremedies.com/ Natural Acne Treatment www.quickacneremedy.com Natural essentials Acne www.naturalessentials.com Natural Solution to Skin Care www.dermae.net Net doctor UK www.netdoctor.co.uk New Zealand Dermatological Society www.dermnetnz.org nlm.nih.gov www.nlm.nih.gov Noixia - Acne Self Help www.noixia.com Nummular dermatitis http://en.wikipedia.org/wiki/Nummular_dermatitis Oxizit Acne Prevention Soap www.oxzit.com Pharma-help Drug Information www.pharma-help.com Physician and Lawyer Directory www.dr-411.com Physician Locator www.fasthealth.com Physician-Patient Communications Network www.medem.com Pimple http://en.wikipedia.org/wiki/Pimples Pioneer Thinking Lotions www.pioneerthinking.com Plastic Surgery: Acne Scars and General Scar www.wellnesskliniek.com Plastic surgery information service, Acne and its canoe.talksurgery.com Proactiv Solution www.proactiv.com Proactiv Solution www.acne.com Q fever http://en.wikipedia.org/wiki/Q_fever Quick Acne Remedy www.quickacneremedy.com Quick care skin-acne www.quickcare.org Refresh Herbal Acne Control www.herbalamerica.com Remedy Find www.remedyfind.com Rodan and Fields Calm Regimen www.rodanandfields.com Skin care advice www.skinxpert.com Skin Care Products www.murad.com Skin care products www.skintactix.com Skin Care Products www.homepeels.com Skin Care RX www.skincarerx.com Skin Chic www.skin-chic.com Skin Clinic Acne www.skinclinic.com Skin Expert Net www.skinexpert.net Skin Health Forum www.skincell.org Soaps and clothing cleansers for acne www.kaviskin.com Teddy care Acne www.teddycare.com UPCMD Medical Directory www.upcmd.com Vita Moor Acne Product www.vitamoor.com Vitamin World www.vitaminworld.com Vitamins - Vita Cure B5 Clear Skin www.b5clearskin.com WebMD www.webmd.com What Are Acne Scars? - Acne - iVillage Beauty Skin beauty.ivillage.com/skin WPXI - Health - New Laser Procedure Treats Acne www.wpxi.com Xian - Chinese Acne Treatment www.acne.bz Youth Information Acne and Spots www.youthinformation.com Zenmed Derma Cleanse System www.zenmed.com Acne Treatment TypesThere are many products available for the treatment of acne, many of which are without any scientifically-proven effects. Generally speaking, successful treatments show little improvement within the first two weeks, instead taking a period of approximately three months to improve and start flattening out. Many treatments that promise big improvements within two weeks are likely to be largely disappointing. However, short bursts of cortisone can give very quick results, and other treatments can rapidly improve some active spots, but usually not all active spots. Modes of improvement are not necessarily fully understood but in general treatments are believed to work in at least 4 different ways (with many of the best treatments providing multiple simultaneous effects): 1. normalising shedding into the pore to prevent blockage 2. Killing P. acnes 3. Anti-inflammatory effects 4. Hormonal manipulation. A combination of treatments can greatly reduce the amount and severity of acne in many cases. Those treatments that are most effective tend to have greater potential for side effects and need a greater degree of monitoring, so a step-wise approach is often taken. Many people consult with doctors when deciding which treatments to use, especially when considering using any treatments in combination.Acne vulgarisAcne vulgaris (commonly called acne) is a skin disease caused by changes in the pilosebaceous units (skin structures consisting of a hair follicle and its associated sebaceous gland). Severe acne is inflammatory, but acne can also manifest in noninflammatory forms. Acne lesions are commonly referred to as pimples, spots, or zits. Acne is most common during adolescence, affecting more than 85% of teenagers, and frequently continues into adulthood. For most people, acne diminishes over time and tends to disappear—or at the very least decrease—after one reaches his or her early twenties. There is, however, no way to predict how long it will take to disappear entirely, and some individuals will continue to suffer well into their thirties, forties and beyond. The face and upper neck are the most commonly affected, but the chest, back and shoulders may have acne as well. The upper arms can also have acne, but lesions found there are often keratosis pilaris, not acne. Typical acne lesions are comedones, inflammatory papules, pustules and nodules. Some of the large nodules were previously called "cysts" and the term nodulocystic has been used to describe severe cases of inflammatory acne. Aside from scarring, its main effects are psychological, such as reduced self-esteem[5] and, according to at least one study, depression or suicide. Acne usually appears during adolescence, when people already tend to be most socially insecure. Early and aggressive treatment is therefore advocated by some to lessen the overall impact to individuals. wiki Acne vulgarisBenzoyl peroxideBenzoyl peroxide cream is a Topical bactericidals. Widely available OTC bactericidal products containing benzoyl peroxide may be used in mild to moderate acne. The gel or cream containing benzoyl peroxide is rubbed, twice daily, into the pores over the affected region. Bar soaps or washes may also be used and vary from 2 to 10% in strength. In addition to its therapeutic effect as a keratolytic (a chemical that dissolves the keratin plugging the pores) benzoyl peroxide also prevents new lesions by killing P.acnes. In one study, roughly 70% of participants using a 10% benzoyl peroxide solution experienced a reduction in acne lesions after 6 weeks.Unlike antibiotics, benzoyl peroxide has the advantage of being a strong oxidizer (essentially a mild bleach) and thus does not appear to generate bacterial resistance. However, it routinely causes dryness, local irritation and redness. A sensible regimen may include the daily use of low-concentration (2.5%) benzoyl peroxide preparations, combined with suitable non-comedogenic moisturisers to help avoid overdrying the skin. Care must be taken when using benzoyl peroxide, as it can very easily bleach any fabric or hair it comes in contact with.Blue and red light Acne TreatmentIt has long been known that short term improvement can be achieved with sunlight. However, studies have shown that sunlight worsens acne long-term[citation needed]. More recently, visible light has been successfully employed to treat acne (phototherapy) - in particular intense violet light (405-420nm) generated by purpose-built fluorescent lighting, dichroic bulbs, LEDs or lasers. Used twice weekly, this has been shown to reduce the number of acne lesions by about 64%; and is even more effective when applied daily. The mechanism appears to be that a porphyrin (Coproporphyrin III) produced within P. acnes generates free radicals when irradiated by 420nm and shorter wavelengths of light. Particularly when applied over several days, these free radicals ultimately kill the bacteria. Since porphyrins are not otherwise present in skin, and no UV light is employed, it appears to be safe, and has been licensed by the U.S. FDA. The treatment apparently works even better if used with red visible light (660 nanometer) resulting in a 76% reduction of lesions after 3 months of daily treatment for 80% of the patients; and overall clearance was similar or better than benzoyl peroxide. Unlike most of the other treatments few if any negative side effects are typically experienced, and the development of bacterial resistance to the treatment seems very unlikely. After treatment, clearance can be longer lived than is typical with topical or oral antibiotic treatments; several months is not uncommon. The equipment or treatment, however, is relatively new and reasonably expensive to buy initially, although the total cost of ownership can be similar to many other treatment methods (such as the total cost of benzoyl peroxide, moisturiser, washes) over a couple of years of use.CortisoneIf a pimple is large and/or does not seem to be affected by other treatments, a dermatologist may administer an injection of cortisone directly into it, which will usually reduce redness and inflammation almost immediately. This has the effect of flattening the pimple, thereby making it easier to cover up with makeup, and can also aid in the healing process. Side effects are minimal, but may include a temporary whitening of the skin around the injection point; and occasionally a small depression forms, which may persist, although often fills eventually. This method also carries a much smaller risk of scarring than surgical removal.DermatologyThe skin is the largest organ of the body and is the most visible. Although many skin diseases are isolated, some are manifestations of internal disease. Hence, a dermatologist is schooled in aspects of surgery, rheumatology (many rheumatic diseases can feature skin symptoms and signs), immunology, neurology (the "neurocuteaneous syndromes", such as neurofibromatosis and tuberous sclerosis), infectious diseases and endocrinology. osmetic dermatology has long been an important part of the field, and dermatologists have been the primary innovators in this area. In the 1900's dermatologists employed dermabrasion to improve acne scarring and fat microtransfer was used to fill in cutaneous defects. Dermatologists specializing in cosmetic dermatology typically use non-invasive procedures to reverse the signs of aging. Botox has been used since it was FDA approved for the treatment of wrinkles. It is used to minimize wrinkles such as frown lines and crow's feet. Fillers are used to "fill in" lines on the face and to minimize the appearance of wrinkles. Brand names of fillers include Restylane, Perlane, Juvederm, Radiesse and Cosmoplast among many others. Dermatologists are also the pioneers of energy based treatments for the skin and these include lasers, intense pulsed light, radiofrequency, infrared light and photodynamic treatments. wiki DermatologyExternally applied antibioticsExternally applied antibiotics such as erythromycin, clindamycin, Stievamycin, or tetracycline kill the bacteria that are harbored in the blocked follicles. While topical use of antibiotics is equally as effective as oral use, this method avoids possible side effects including upset stomach and drug interactions (e.g. it will not affect use of the oral contraceptive pill), but may prove awkward to apply over larger areas than just the face alone.FollicleA hair follicle is part of the skin that grows hair by packing old cells together. Attached to the follicle is a sebaceous gland, a tiny sebum-producing gland found everywhere except on the palms, lips and soles of the feet. The thicker density of hair, the more sebaceous glands are found. Also attached to the follicle is a tiny bundle of muscle fiber called the arrector pili that is responsible for causing the follicle lissis to become more perpendicular to the surface of the skin, and causing the follicle to protrude slightly above the surrounding skin (piloerection). This process results in goose bumps (or goose flesh). Stem cells are located at the junction of the arrector and the follicle, and are principally responsible for the ongoing hair production during a process known as the Anagen stage. The average growth rate of healthy hair follicles on the scalp is .04 cm per day.Genital wartsGenital warts often occur in clusters and can be very tiny or can spread into large masses in the genital or penis area. In women they occur on the outside and inside of the vagina, on the opening (cervix) to the womb (uterus), or around the anus. They are approximately as prevalent in men, but the symptoms may be less obvious. When present, they usually are seen on the tip of the penis. They also may be found on the shaft of the penis, on the scrotum, or around the anus. Rarely, genital warts also can develop in the mouth or throat of a person who has had oral sex with an infected person. Genital warts may disappear without treatment, but sometimes eventually develop a fleshy, small raised growth. There is no way to predict whether they will grow or disappear. Genital warts (or Condyloma, Condylomata acuminata, or venereal warts) is a highly contagious sexually transmitted infection caused by some sub-types of human papillomavirus (HPV). It is spread through direct skin-to-skin contact during oral, genital, or anal sex with an infected partner.Hormonal Acne treatmentsIn females, acne can be improved with hormonal treatments. The common combined oestrogen/progestogen methods of hormonal contraception have some effect, but the antiandrogen, Cyproterone, in combination with an oestrogen (Diane 35) is particularly effective at reducing androgenic hormone levels. Diane-35 is not available in the USA, but a newer oral contraceptive containing the progestin drospirenone is now available with fewer side effects than Diane 35 / Dianette. Both can be used where blood tests show abnormally high levels of androgens, but are effective even when this is not the case. Along with this, treatment with low dose spironolactone can have anti-androgenetic properties, especially in patients with polycystic ovarian syndrome.IsotretinoinA daily oral intake of vitamin A derivative isotretinoin (marketed as Accutane, Amnesteem, Sotret, Claravis, Clarus) over a period of 4-6 months can cause long-term resolution or reduction of acne. It is believed that isotretinoin works primarily by reducing the secretion of oils from the glands, however some studies suggest that it affects other acne-related factors as well. Isotretinoin has been shown to be very effective in treating severe acne and can either improve or clear well over 80% of patients. The drug has a much longer effect than anti-bacterial treatments and will often cure acne for good. The treatment requires close medical supervision by a dermatologist because the drug has many known side effects (many of which can be severe). About 25% of patients may relapse after one treatment. In those cases, a second treatment for another 4-6 months may be indicated to obtain desired results. It is often recommended that one lets a few months pass between the two treatments, because the condition can actually improve somewhat in the time after stopping the treatment and waiting a few months also gives the body a chance to recover. Occasionally a third or even a fourth course is used, but the benefits are often less substantial. The most common side effects are dry skin and occasional nosebleeds (secondary to dry nasal mucosa). Oral retinoids also often cause an initial flare up of acne within a month or so, which can be severe. There are reports that the drug has damaged the liver of patients. For this reason, it is recommended that patients have blood samples taken and examined before and during treatment. In some cases, treatment is terminated or reduced due to elevated liver enzymes in the blood, which might be related to liver damage. Others claim that the reports of permanent damage to the liver are unsubstantiated, and routine testing is considered unnecessary by some dermatologists. Blood triglycerides also need to be monitored. However, routine testing are part of the official guidelines for the use of the drug in many countries. Some press reports suggest that isotretinoin may cause depression but as of September 2005 there is no agreement in the medical literature as to the risk. The drug also causes birth defects if women become pregnant while taking it or take it while pregnant. For this reason, female patients are required to use two separate forms of birth control or vow abstinence while on the drug. Because of this, the drug is supposed to be given to females as a last resort after milder treatments have proven insufficient. Restrictive rules (see iPledge program) for use were put into force in the USA beginning in March 2006 to prevent misuse, causing occasioned widespread editorial comment.Jock itchTinea cruris is the scientific name for fungal infection of the groin region. Official alternative names include jock itch. As the common name for this condition implies, it causes itching or a burning sensation in the groin area, thigh skin folds, or anus. It may involve the inner thighs and genital areas, as well as extending back to the perineum and perianal areas. Affected areas may appear red, tan, or brown, with flaking, rippling, peeling, or cracking skin. The acute infection begins with an area in the groin fold about a half-inch across, usually on both sides. The area may enlarge, and other sores may develop in no particular pattern. The rash appears as raised red plaques (platelike areas) and scaly patches with sharply defined borders that may blister and ooze. If the rash advances, it usually advances down the inner thigh. The advancing edge is redder and more raised than areas that have been infected longer. The advancing edge is usually scaly, and very easily distinguished or well demarcated. The skin within the border turns a reddish-brown and loses much of its scale. The border may exhibit tiny pimples or even pustules, with central areas that are reddish and dry with small scales. If infected with candidal organisms, the rash tends to be redder and wetter. Opportunistic infections (infections that are caused by a diminished immune system) are frequent. Fungus from other parts of the body (commonly tinea pedis or 'athlete's foot') can contribute to jock itch. A warm, damp environment allowing the fungus to cultivate greatly contributes; especially with tight, sweaty or rubbing clothing such as a jockstrap.KeloideloidA keloid is a type of hypertrophic scar with mainly type I and some type III collagen which results in an overgrowth of tissue at the site of a healed skin injury. Keloids are firm, rubbery lesions or shiny, fibrous nodules, and can vary from pink to flesh-colored or red to dark brown in color. A keloid scar is benign, non-contagious, and usually accompanied by severe itchiness, sharp pains, and changes in texture. In severe cases, it can affect movement of skin. Keloids expand in claw-like growths over normal skin. They have the capability to hurt with a needle-like pain or to itch without warning, although the degree of sensation varies from patient to patient. wiki KeloideloidLaser Acne treatmentLaser surgery has been in use for some time to reduce the scars left behind by acne, but research has been done on lasers for prevention of acne formation itself. The laser is used to produce one of the following effects: to burn away the follicle sac from which the hair grows, to burn away the sebaceous gland which produces the oil to induce formation of oxygen in the bacteria, killing them. Since lasers and intense pulsed light sources cause thermal damage to the skin, there are concerns that laser or intense pulsed light treatments for acne will induce hyperpigmented macules (spots) or cause long-term dryness of the skin. In the United States, the FDA has approved several companies, such as Candela Corp., to use a cosmetic laser for the treatment of acne. However, efficacy studies have used very small sample sizes (fewer than 100 subjects) for periods of six months or less, and have shown contradictory results. Laser treatment being relatively new, protocols remain subject to experimentation and revision, and treatment can be quite expensive. Also, some Smoothbeam laser devices had to be recalled due to coolant failure, which resulted in painful burn injuries to patients.MelanomaMelanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye. It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells, called melanocytes. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm. Around 160,000 new cases of melanoma are diagnosed worldwide each year, and it is more frequent in males and caucasians. It is more common in caucasian populations living in sunny climates than other groups. According to a WHO Report about 48,000 melanoma related deaths occur worldwide per annum. wiki MelanomaNummular dermatitisNummular dermatitis, also known as nummular eczema, is one of the many forms of dermatitis. Also known as discoid dermatitis, it is characterized by round or oval-shaped itchy lesions. The coin-shaped patches can affect any part of the body, but the legs and buttocks are the most common areas. Flare-ups are associated with dry skin, so the winter season is a particularly bad time for those with this condition. The disorder is recurrent and chronic, and may appear at any age, although it is most common in people in their 60's. Nummular dermatitis does not appear to be a genetic condition, is not related to food allergies, and is not contagious. wiki Nummular dermatitisOral antibioticsOral antibiotics used to treat acne include erythromycin or one of the tetracycline antibiotics (tetracycline, the better absorbed oxytetracycline, or one of the once daily doxycycline, minocycline, or lymecycline). Trimethoprim is also sometimes used (off-label use in UK). However, reducing the P. acnes bacteria will not, in itself, do anything to reduce the oil secretion and abnormal cell behaviour that is the initial cause of the blocked follicles. Additionally the antibiotics are becoming less and less useful as resistant P. acnes are becoming more common. Acne will generally reappear quite soon after the end of treatment—days later in the case of topical applications, and weeks later in the case of oral antibiotics. Furthermore side effects of tetracycline antibiotics can include yellowing of the teeth and an imbalance of gut flora, so are only recommended after topical products have been ruled out. It has been found that sub-antimicrobial doses of antibiotics such as minocycline also improve acne. It is believed that minocycline's anti-inflammatory effect also prevents acne. These low doses do not kill bacteria and hence cannot induce resistance.Phototherapy Acne TreatmentIt has long been known that short term improvement can be achieved with sunlight. However, studies have shown that sunlight worsens acne long-term[citation needed]. More recently, visible light has been successfully employed to treat acne (phototherapy) - in particular intense violet light (405-420nm) generated by purpose-built fluorescent lighting, dichroic bulbs, LEDs or lasers. Used twice weekly, this has been shown to reduce the number of acne lesions by about 64%; and is even more effective when applied daily. The mechanism appears to be that a porphyrin (Coproporphyrin III) produced within P. acnes generates free radicals when irradiated by 420nm and shorter wavelengths of light. Particularly when applied over several days, these free radicals ultimately kill the bacteria. Since porphyrins are not otherwise present in skin, and no UV light is employed, it appears to be safe, and has been licensed by the U.S. FDA. The treatment apparently works even better if used with red visible light (660 nanometer) resulting in a 76% reduction of lesions after 3 months of daily treatment for 80% of the patients; and overall clearance was similar or better than benzoyl peroxide. Unlike most of the other treatments few if any negative side effects are typically experienced, and the development of bacterial resistance to the treatment seems very unlikely. After treatment, clearance can be longer lived than is typical with topical or oral antibiotic treatments; several months is not uncommon. The equipment or treatment, however, is relatively new and reasonably expensive to buy initially, although the total cost of ownership can be similar to many other treatment methods (such as the total cost of benzoyl peroxide, moisturiser, washes) over a couple of years of use.PimpleA pimple is a result of a blockage of the skin's pore. It can be a pustule or papule. Causes Inside the pore are sebaceous glands which produce sebum. When the outer layers of skin shed (as they do continuously), the dead skin cells left behind may become 'glued' together by the sebum. This causes a blockage in the pore, especially when the skin becomes thicker at puberty. The sebaceous glands produce more sebum which builds up behind the blockage, and this sebum harbours various bacteria including the species Propionibacterium acnes. Pimples can often be caused by stress. wiki PimpleQ feverQ fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects both humans and animals. This organism is uncommon but may be found in cattle, sheep, goats and other domestic mammals, including cats and dogs. The infection results from inhalation of contaminated particles in the air, and from contact with the vaginal mucus, milk, feces, urine or semen of infected animals. The incubation period is 9-40 days. It is considered possibly the most infectious disease in the world, as a human being can be infected by a single bacterium. wiki Q feverRetinoids Topical Acne TreatmentRetinoids are A group of medications for normalizing the follicle cell lifecycle are topical retinoids such as tretinoin (brand name Retin-A), adapalene (brand name Differin), and tazarotene (brand name Tazorac). Like isotretinoin, they are related to vitamin A, but they are administered as topicals and generally have much milder side effects. They can, however, cause significant irritation of the skin. The retinoids appear to influence the cell creation and death lifecycle of cells in the follicle lining. This helps prevent the hyperkeratinization of these cells that can create a blockage. Retinol, a form of vitamin A, has similar but milder effects and is used in many over-the-counter moisturizers and other topical products. Effective topical retinoids have been in use over 30 years but are available only on prescription so are not as widely used as the other topical treatments. Topical retinoids often cause an initial flare up of acne and facial flushing.Sebaceous glandsSebaceous glands secrete an oily substance called sebum (Latin, meaning fat or tallow) that is made of fat (lipids) and the debris of dead fat-producing cells. In the glands, sebum is produced within specialized cells and is released as these cells burst; sebaceous glands are thus classified as holocrine glands. Sebum itself is odorless, but its bacterial breakdown can produce odors. Sebum is one cause of some people experiencing "oily" hair or skin if not washed for several days. Earwax is partly composed of sebum. Sebum acts to protect and waterproof hair and skin, and keep them from becoming dry, brittle, and cracked. It can also inhibit the growth of microorganisms on skin. Sebaceous glands are a branched type of acinar gland, these glands exist in humans throughout the skin except in the palms of the hands and soles of the feet. Sebaceous glands can usually be found in hair-covered areas, where they are connected to hair follicles. The glands deposit sebum on the hairs, and bring it to the skin surface along the hair shaft. The structure consisting of hair, hair follicle, arrector pili muscle, and sebaceous gland is known as a pilosebaceous unit. Sebaceous glands are also found in non-haired areas (glabrous skin) of eyelids, penis, labia minora, and nipples. Here, the sebum traverses ducts which terminate in sweat pores on the surface of the skin. Pores range in size from 50 to 80 μm on average. The inner surface of the lip and the buccal surface of the cheek can potentially contain ectopic sebaceous glands commonly known as Fordyce's spots or Fordyce granules. These occur as yellowish circular dots that form clusters. 80 percent of the population have Fordyce granules and these sebaceous glands are asymptomatic. At the rim of the eyelids, meibomian glands are a specialized form of sebaceous gland. They secrete sebum into the tears coating the eye, to slow evaporation.Topical bactericidalsWidely available OTC bactericidal products containing benzoyl peroxide may be used in mild to moderate acne. Other antibacterials that have been used include triclosan, or chlorhexidine gluconate but these are often less effective, but also have fewer side-effects.UrticariaUrticaria or hives is a skin condition, commonly caused by an allergic reaction, that is characterized by raised red skin wheals (welts). It is also known as skin-disease-itis or uredo. Wheals from urticaria can appear anywhere on the body, including the face, lips, tongue, throat, and ears. The wheals may vary in size from about 5 mm (0.2 inches) in diameter to the size of a dinner plate; they typically itch severely, sting, or burn, and often have a pale border. Urticaria is generally caused by direct contact with an allergenic substance, or an immune response to food or some other allergen, but can also appear for other reasons, notably emotional stress. The rash can be triggered by quite innocent events, such as mere rubbing or exposure to cold.VitiligoVitiligo or leukoderma is a chronic skin disease that causes loss of pigment, resulting in irregular pale patches of skin. The precise cause of vitiligo is complex and not fully understood. There is some evidence suggesting it is caused by a combination of auto-immune, genetic, and environmental factors. The population incidence worldwide is considered to be between 1% and 2%. According to Diseases Database it is disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. Half of people with vitiligo develop patches of de-pigmented skin appearing on extremities before their 20s. The patches may grow, shrink, or remain constant in size. Patches often occur symmetrically across both sides on the body. Occasionally small areas may repigment as they are recolonised by melanocytes. The location of vitiligo affected skin changes over time, with some patches re-pigmenting and others becoming affected.WartsA wart is generally a small, rough tumor, typically on hands and feet but often other locations, that can resemble a cauliflower or a solid blister. Warts are common, and are caused by a viral infection, specifically by the human papillomavirus and are contagious when in contact with the skin of an infected person. It is also possible to get warts from using towels or other objects. They typically disappear after a few months but can last for years and can recur.XerodermaXeroderma pigmentosum, or XP, is an autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet (UV) light is deficient. This disorder leads to multiple basaliomas and other skin malignancies at a young age. In severe cases, it is necessary to avoid sunlight completely. The two most common causes of death for XP victims are metastatic malignant melanoma and squamous cell carcinoma.Y chromosomeThe Y chromosome is the sex-determining chromosome in most mammals, including humans. In mammals, it contains the gene SRY, which triggers testis development, thus determining sex. The human Y chromosome is composed of about 60 million base pairs. Most mammals have one pair of sex chromosomes in each cell (though for example the platypus has five pairs). Males have one Y chromosome and one X chromosome, while females have two X chromosomes. In mammals, the Y chromosome contains the gene that triggers embryonic development as a male. This gene is SRY. Other genes (in addition to SRY) on the Y chromosomes of men and other mammals are needed for normal sperm production.ZitsZits are what happen when the oil glands in your skin get clogged and pus is what comes out. Zits do not care about color, sex, or age, everyone from teenagers to grannies get zits. In fact, zits can be found on the faces and bodies of over 70 million people! A lot of things can cause zits. Including stress, and a build-up of toxins including infection. Stress is not just a mental state of being, it can also affect your physical wellness. If you have an infection, it will find an outlet through pimples. |
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