Drug Famotidine Preservative Free From Pfizer With Famotidine 10mg/ml

The Ingredients: Famotidine
Dosage Form and Administration: Injectable; Injection
Drug Trade Name: Famotidine Preservative Free
Firm: Pfizer
Strength: 10MG/ML
New Drug Application Type: A
The Drug Application Number:78642
Medicine Product Number: 1
Approval Date: 6/25/2008
Reference Listed Drug: No
Type: RX
Applicant Full Name: Pfizer Inc

Topical Bactericidals

Widely available over-the-counter (OTC) bactericidal products containing benzoyl peroxide treat mild to moderate acne. Other anti-bacterials are triclosan, or chlorhexidine gluconate, but these are often less effective despite having fewer side effects.

What Is Sleep?

For a long time, people considered sleep a uniform block of time when a person was not awake. Thanks to sleep studies done over the past several decades, people now know that sleep has distinct stages that cycle throughout the night in predictable patterns. How well rested a person is and how well a person functions depend not just on the total sleep time but on how much of the various stages of sleep a person gets each night.
The brain stays active throughout sleep and each stage of sleep appears as a distinctive pattern of electrical activity known as brain waves.
Sleep occurs in two basic types: rapid eye movement (REM) sleep and non-REM sleep (with four different stages). (See "Types of Sleep"). Typically, sleep begins with non-REM sleep. In stage 1 non-REM sleep, a person sleeps lightly and wakes easily by noises or other disturbances. During this first stage of sleep, the eyes move slowly and muscle activity slows. A person then enters stage 2 non-REM sleep, when eye movements stop. The brain shows a distinctive pattern of slower brain waves with occasional bursts of rapid waves.
When a person progresses into stage 3 non-REM sleep, brain waves become even slower; although brain waves will still occur in smaller, faster waves. By stage 4 non-REM sleep, the brain produces extremely slow waves almost exclusively. In stages 3 and 4, the person is in deep sleep, during which it is very difficult to wake up. Children who wet the bed or sleep walk tend to do so during stages 3 or 4 of non-REM sleep. Deep sleep is the "restorative" part of sleep that is necessary for feeling well rested and energetic during the day.

Types of Sleep

Non-REM Sleep

REM Sleep

Stage 1: Light sleep; easily awakened; muscle activity; eye movements slow down.

Usually first occurs about 90 minutes after a person falls asleep; cycles along with the non-REM stages throughout the night. Eyes move rapidly, with eyelids closed. Breathing is more rapid, irregular and shallow. Heart rate and blood pressure increase. Dreaming occurs. Arm and leg muscles temporarily paralyzed.

Stage 2: Eye movements stop; slower brain waves, with occasional bursts of rapid brain waves.

Stage 3: Considered deep sleep; difficult to wake; brain waves slow down more, but still have occasional rapid waves.

Stage 4: Considered deep sleep; difficult to wake; extremely slow brain waves.

During REM sleep, the eyes move rapidly in various directions, even though the eyelids remain closed. Breathing also becomes more rapid, irregular and shallow and the heart rate and blood pressure increase. Dreaming typically occurs during REM sleep. During this type of sleep, arm and leg muscles feel tem­porarily paralyzed so that a person cannot "act out" any dreams that he or she may be having.
The first period of REM sleep people experience usually occurs about an hour to an hour and a half after falling asleep. After that, the sleep stages repeat themselves continuously during sleep. As the night progresses, REM sleep time becomes longer, while time spent in non-REM sleep stages 3 and 4 becomes shorter. By morning, nearly all sleep time occurs in stages 1 and 2 of non-REM sleep and in REM sleep. If something disrupts REM sleep during one night, REM sleep time is typically longer than normal in subsequent nights. Overall, almost one-half of total sleep time occurs as stages 1 and 2 non-REM sleep and about one-fifth each as deep sleep (stages 3 and 4 of non-REM sleep) and REM sleep. In contrast, infants spend half or more of their total sleep time in REM sleep. Gradually, as infants mature, the percentage of total sleep time that is REM progressively decreases to reach the one-fifth level typical of later childhood and adulthood.
Doctors do not fully understand why people dream and why REM sleep is so important. Sleep specialists know that REM sleep stimulates the brain regions used in learning and the laying down of memories. Animal studies suggest that dreams may reflect the brain sorting and selectively storing important new information acquired during wake time. While the brain processes this information, the brain might also revisit scenes from the day while pulling up older memories. This process may explain why childhood memories can be interspersed with events that are more recent.