Hormonal Acne Treatments
In females, hormonal treatments can improve acne. The common combined oestrogen and progestogen methods of hormonal contraception have some effect, but the antiandrogen, Cyproterone, in combination with an oestrogen (Diane-35) is particularly effective at reducing androgenic hormone levels. Diane-35 is not available in the USA, but a newer oral contraceptive containing the progestin drospirenone is now available with fewer side effects than Diane-35 or Dianette. Diane-35 is effective where blood tests show abnormally high levels of androgens. Along with this, treatment with low dose spironolactone can have anti-androgenetic properties, especially in patients with polycystic ovarian syndrome.
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